Contribution of Disulfiram Use to Retain Alcohol-Dependent Outpatients in Treatment: A Focus on Gender

Márcia F Elbreder, Rebeca S e Silva and Ronaldo Laranjeira

Affiliation : Federal University of São Paulo, São Paulo, Brazil

Although alcoholism is a severe public health problem having a worldwide impact, there are a limited number of pharmacological interventions used for its treatment.

To evaluate the contribution of disulfiram use for retention of alcohol-dependent outpatients in treatment with focus on gender.

This is a retrospective cross-sectional study using a sample of 810 alcohol-dependent patients (652 men and 158 women) who attended the clinic between 2000 and 2006. The patients were divided into three groups depending on their treatment retention.

A greater concentration of men and women who took the aversive medication among the patients remained longer in treatment.

Disulfiram is an instrument that can contribute to improve retention in outpatient treatment, but this approach should be viewed as part of a complex and dynamic therapeutic process.

Correspondence: Márcia F Elbreder, Alcohol and Drugs Research Unit (UNIAD), R Botucatu 394, V. Clementino, CEP 04023-061, São Paulo, SP, Brazil. phone and fax: (005511) 5575-1708, e-mail: [email protected]


Please sign in to read the full article.

Leave a Reply

Your email address will not be published. Required fields are marked *